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Omega-3 fatty acids Chronic inflammation can contribute to oxidative stress and deplete glutathione reserves [50]

They function as cellular messengers, regulating a wide range of physiological processes including hormone function, metabolism, immune response, and tissue repair

Also, prospective studies confirm the inverse association of IGF-1 with systolic blood pressure and significantly reduced risk for incident hypertension in non-diabetic female subjects ( 4.1.4 IGF-1, diabetes, and hyperinsulinemia A link between decreased circulating IGF-1 and MetS components, such as dyslipidemia and DM, has been observed (161) but remains questionable due to conflicting findings in the literature