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(2017) discovered that biomarkers associated with cellular senescence were detectable in IPF tissues, that the expression of cyclin-dependent kinase inhibitor 2A (CDKN2A), a marker of cellular senescence, increased with the severity of fibrosis, and that low expression of CDKN2A contributed to the restoration of healthy lungs in IPF mice

doi: 10.1161/jaha.117.008178 38 PulversKNollenNLRiceMSchmidCHQuKBenowitzNLet al

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