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It does not

doi: 10.1080/02640414.2016.1261176

Tesamorelin is a GHRH analog and ipamorelin is a ghrelin-mimetic GH secretagogue

Heffernan MA, Thorburn AW, Fam B, et al

Clinical evidence: The SURMOUNT-1 trial, published in the New England Journal of Medicine , showed that participants on the highest dose of tirzepatide (15 mg) lost an average of 22.5 percent of their body weight over 72 weeks the most weight loss ever demonstrated by a pharmaceutical agent in a clinical trial (Jastreboff et al., 2022)