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[Abstract]2024 Sep 7:S1995-820X(24)00140-8

Cancers (Basel), 11 , 4

These cytokines not only directly damage chondrocytes but also act back on the synovium and other chondrocytes, creating a self-amplifying vicious cycle of inflammation along the cartilage-synovium axis

Instead, cells undergoing ferroptosis have only subtle differences in their morphological features, like smaller-than-normal cell volume and increased mitochondrial membrane density

The in vitro component demonstrated that both glucagon and Retatrutide directly decreased ANGPTL3/8 secretion from hepatocytes, and this effect was blocked by a glucagon receptor (GCGR) antagonist