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In vitro , high iron level have been shown to directly stimulate the proliferation of human lung fibroblasts and enhance the secretion of ECM and pro-inflammatory factors (107)

Stasi, C., Fallani, S., Voller, F

10.1182/blood-2006-07-035972

Neurosurgery 87, 11911198

82 However, overexpression of only TET1 and TET2 can cause a global decrease of 5-mC

In view of the dependence of cancer cells on glutamine metabolism, targeted therapies for glutamine metabolism have been developed, from glutamine uptake to glutamine catalytic enzyme