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In parallel, its association with vascular processes, the organisation of the tissue environment and the course of regeneration in experimental models is indicated

These include: Inappropriate dosing or frequency Lack of proper diagnosis and monitoring Non-sterile injection technique increasing infection risk Absence of medical supervision for adverse reactions Financial cost without clinical benefit Patients should report any suspected adverse reactions to B12 injections via the MHRA Yellow Card scheme

These factors should be considered when translating our study results into patient care

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Of these, 9% of patients had Grade III or IV chondral lesions and were under 50 years old, meeting conservative indications for cartilage repair surgery

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