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GSH levels have been reported to be reduced in a mouse model of middle cerebral artery occlusion where the infarct size was reduced following intervention with the ferroptosis-related inhibitors, liproxstatin-1 and ferrostatin-1 (46)

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When PTU was given to hypothyroidism control experimental rats, it probably inhibited the synthesis of protein which in turn decreased the thyroxine-binding globulin (Reference Kochman, Jakubczyk and Bargiel3,Reference Seven, Seymen and Hatemi21Reference Sharsher, Ahmed and Metwally24,Reference Lewicki, Lesniak and Bertrandt42)