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10.1016/j.jep.2024.117868 106 LuX.JiQ.PanH.FengY.YeD.GanL.et al (2024)

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Adequate Sleep Getting enough quality sleep is crucial for overall health and supports optimal glutathione production in the body

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Moreover, PER2 has been reported to form a trimeric complex with p53 and the oncogenic mouse double minute-2 homolog protein (MDM2), the p53s negative regulator, thereby increasing p53 stability by blocking Mdm2-dependent ubiquitination and transcription of p53 target genes 36

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