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Rare Disease Education: Pernicious Anemia Editor: Kelsey LaFayette, DNP, RN, FNP-C "When you hear hoofbeats, think of horses, not zebras, is a common saying in medical education that means you should think of common conditions first, instead of rare ones, in making a diagnosis

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doi:10.4049/jimmunol.1500460 Zdrenghea MT, Makrinioti H, BagaceanC, Bush A, Johnston SL, Stanciu LA

Moreover, we observed an ordered loop in the fully active state, located in the opposite site of the adenosine triphosphate (ATP)-binding pocket, whereas the loop is disordered in the intermediate state and in the soluble mTORC1RHEB structure (Extended Data Fig

4.5 Deep eutectic solvent extraction method Deep eutectic solvents are mainly composed of hydrogen bond donors such as polyols, urea and carboxylic acids and hydrogen bond acceptors such as quaternary ammonium salts (such as choline chloride)