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10.1016/j.ijbiomac.2019.06.136 123 ZengT.WangX.WangW.FengQ.LaoG.LiangY.et al (2019)

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For example, when human Sirt1 was incubated with acetylated human core histones purified from HeLa cells, the acetyl group at H4K16 was more efficiently removed by Sirt1 than that at H3K9 11

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Beyond its role as an absorption enhancer, bromelain is a potent systemic anti-inflammatory agent

However, future studies are required to experimentally demonstrate this notion