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Emerging literature suggests that immune cell mitochondrial health is compromised in PD models

Hypercholesterolemia occurs in 1660%, whereas hypertriglyceridemia is reported in 736% of cases [269, 270]

Both native cardiac myocytes and pulmonary artery endothelial cells overexpressing AC6 are inhibited by the NO donor S-nitroso-N-acetylpenicillamine (SNAP), inhibiting both basal and FSK-stimulated cAMP production (Ostrom et al., 2004)

Decades of research in pursuit of such a singularity has, however, uncovered common themes between select subgroups of mutant proteins, which may collectively be predictive of the propensity for all mutant proteins to misfold

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Kluczowe zastrzeenie: zdecydowana wikszo tych danych pochodzi z bada na szczurach i myszach oraz z bada in vitro