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SKU: 76627070243 · From reganhouse.co.nz

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Description

Shelton JF, Shastri AJ, Fletez-Brant K, Aslibekyan S, Auton A (2022) The UGT2A1/UGT2A2 locus is associated with COVID-19-related loss of smell or taste

gingivalis synergistically regulates three core pathways via the TLR4/NF-B signaling pathway: (1) iron metabolism imbalance (upregulation of TFRC and NCOA4 expression leading to intracellular iron overload), (2) lipid metabolism reprogramming (enhanced ACSL4 and LPCAT3 activity promoting polyunsaturated fatty acid phospholipid accumulation), (3) antioxidant defense collapse (downregulation of SLC7A11 and GPX4 triggering glutathione depletion and impaired lipid peroxide clearance)