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Glycemic mechanism and insulin sparing sensitization not secretion: fasting insulin and C-peptide fall while insulin sensitivity (HOMA2-%S) rises +31.8/+43.2/+49.9% (SURPASS J-mono, Hamamoto 2025)

Studies on GLP-1 receptor agonist users show mixed results: some patients maintain normal B12 levels, while othersparticularly those with pre-existing absorption issues, vegans, or those on long-term metforminmay develop subclinical B12 deficiency

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Biochemistry 5 edn, (W H Freeman, 2002)

Phytother Res 31:340344 Machova Urdzikova L, Cimermanova V, Karova K, Dominguez J, Stepankova K, Petrovicova M, Havelikova K, Gandhi CD, Jhanwar-Uniyal M, Jendelova P (2023) The role of green tea catechin epigallocatechin gallate (EGCG) and mammalian target of rapamycin (mTOR) inhibitor PP242 (Torkinib) in the treatment of spinal cord injury

Source: Sonthalia et al., 2016 It works