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Mean pixel intensities at 405 and 488 nm were quantified via Fiji/ImageJ and the ratio 488/405 nm was calculated

To date, results from the phase III clinical trials showed that both the Pfizer/BioNTech (BNT162b2) and Moderna (mRNA-1273) mRNA vaccines achieved 9095% efficacy in protecting against COVID-19 (refs 1,2 ), while the AdV vaccines (ChAdOx1 nCoV-19) and Gam-COVID-vac (Sputnik V) showed protection at a slightly lower efficacy (average 70% and 91%, respectively) 3,4

Cancers (Basel) 12(2):310 Okazaki A, Gameiro PA, Christodoulou D (2017) Glutaminase and poly(ADP-ribose) polymerase inhibitors suppress pyrimidine synthesis and VHL-deficient renal cancers

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Mechanistically, NGB also binds released cytochrome-c, blocking apoptosome formation (caspase-9 activation) and preventing intrinsic apoptosis under oxidative/hypoxic stress principles well-described in neurons and relevant to hepatic injury [128]