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Inhibiting P300 and knocking down STEAP3 both block the repair effect of lactate

Iwaoka M, Katakura A, Mishima J et al (2015) Mimicking the lipid peroxidation inhibitory activity of phospholipid hydroperoxide glutathione peroxidase (GPx4) by using fatty acid conjugates of a water-soluble selenolane

[9,10,22,24,25,27,28,42, 43, 44, 45, 46] The target immune cells in this strategy are autoreactive T cells, regulatory T cells (T regs ), and tolerogenic dendritic cells (tol DCs), as schematized in Figure 1 for SLE