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Frequent blood transfusions, which can cause iron overload and affect nutrient regulation

154 There is increasing evidence supporting the intimate participation and pivotal regulation of the LOX AA pathway in I/R injury in enzymatic and nonenzymatic manners

Superoxide dismutase activity Superoxide dismutase (SOD) is an endogenous scavenger of reactive oxygen species (ROS) and is one of the major antioxidant enzymes involved in protecting the nerve tissue from oxidative stress