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However, during a severe viral infection or prolonged periods of chronic inflammation, this vital defense system can become overwhelmed and depleted

doi: 10.1016/j.addr.2022.114293

D.CarusoG.FlorisR.et al

10.1007/s11596-014-1358-1 184 ZhouX.LuQ.KangX.TianG.MingD.YangJ

Figure 2 3.1 Xc _ /GSH/GPX4 axis GPX (glutathione peroxidase) is a protein superfamily that consists of eight isoforms in mammals, with only five of them (GPX 14 and 6) being seleno-proteins, while GPX 5,7,8 are non-seleno proteins (54)