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Reduced energy production: Mitochondrial dysfunction leads to fatigue, cognitive decline and metabolic disorders

JACC Basic Transl Sci 3(4):503517

Further research is needed to fully understand the extent of the health benefits of beetroot, but the current evidence suggests that it is a promising food for improving cardiovascular health

Haque R, Shamsuzzama, Kumar L, Sharma T, Fatima S, Jadiya P et al (2020) Human insulin modulates -synuclein aggregation via DAF-2/DAF-16 signalling pathway by antagonising DAF-2 receptor in C

For example, the triphenylphosphonium-modified copper complex TPP-CuET accumulates in mitochondria and disrupts the TCA cycle, ATP synthesis, and electron transport, thus amplifying immunogenic cuproptosis

Fecal matter from metformin-treated mice attenuates intestinal ferroptosis induced by IIRI To investigate the role of the gut microbiota in the anti-ferroptosis effect of metformin, we established a dirty cage group by allowing mice to feed on metformin-modulated feces from the MET group