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Born and raised outside Houston, he gained early acclaim for his piercing introspection and absorbing narratives, but over the course of five solo albums, he flirted with everything from Paul Simon and John Prine to Elton John and Joni Mitchell in a series of sonic and visual transformations that ran the gamut from Redneck Steely Dan to Lone Star Liberace

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This glycoprotein has been extensively studied, particularly in MM, leading to the development of several drugs based on monoclonal antibodies targeting CD38, such as daratumumab and isatuximab