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Moreno-Merlo F, Wanless IR, Shimamatsu K, Sherman M, Greig P, Chiasson D

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4.2.1 Core cell types and their roles Macrophages are key effector cells in emphysema development, degrading elastic fibers of alveolar walls by secreting MMP-9 and MMP-12

218 In another placebo-controlled trial in 48 subjects who were overweight or obese, 1,000 mg pomegranate extract for 30 days reduced inflammatory marker levels and improved blood glucose, insulin, and LDL-cholesterol levels