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However, the Liver Tox Knowledge Base (LTKB) may provide more insight into adverse drug reactions in DILI research [255] and allow medical professionals to distinguish DILI caused by agents with different latencies, symptoms, mechanisms, and responses [346]

The reduced expression of H3K18la specifically decreases ferroptosis driver genes [activating transcription factor (ATF3), ATF4 and ChaC glutathione specific gamma-glutamylcyclotransferase 1 (CHAC1)], thereby inhibiting ferroptosis (66)

Wang X, Chi N, Tang X

Bisdemethoxycurcumin (BDMC), a CU analog that retains the 1,3 diketone moiety, has been shown to protect neurons from oxidative stress damage by activating SIRT1 expression, suggesting its potential as a therapeutic compound for AD (Xu et al., 2020)