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While numerous studies have identified and investigated oxidative stress by detecting cellular ROS, it is crucial to recognize that an imbalance in the oxidative state of a single organelle can result in oxidative damage to the entire cell

Milam JE, Keshamouni VG, Phan SH, Hu B, Gangireddy SR, Hogaboam CM, et al

The lysate was cleared by centrifugation and the protein was purified by Ni-His-affinity chromatography in batch mode

doi: 10.1089/ars.2017.7440 138 WangX.ZhengC.YaoH.GuoY.WangY.HeG.et al

doi: 10.18632/oncotarget.6438

BHB supports mitochondrial metabolism In light of the ability of BHB to alter the functionality of CD4 + T cells, we used extracellular flux analysis