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Omic approaches used in toxicology provide a tool to characterize and quantify the molecular and biochemical changes in cells, tissues and organisms following exposure to chemicals and toxic substances

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Additionally, studies have shown that activated immune cells (including central glial cells) can release pro-inflammatory cytokines such as IL-1, IL-6 and TNF-

C-reactive protein promotes the expansion of myeloid derived cells with suppressor functions

J Thorac Oncol 8(4):502-10, 2013

These observations support the critical role of autophagy for cell survival under normal conditions and during APAP-induced liver injury