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8 When APAP is administered at therapeutic doses under normal physiological conditions, the remaining 510% of the drug is metabolized in hepatocytes by cytochrome P450 enzymes such as CYP2E1 and CYP1A2 through phase I enzymatic reactions, resulting in the generation of the toxic reactive metabolite NAPQI (Fig

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I recommend digging into root cause factors such as not consuming enough dietary sources of this vitamin, as well as underlying issues that may be impairing the absorption of B12 (such as H