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Development and validation of a nomogram for preoperative prediction of lymph node metastasis in early gastric cancer

Finally, under the weakly acidic condition characteristic of the TME, HK molecules are released from the NPs in a controlled manner, thereby maintaining a sustained drug concentration within the tumor cells and exerting its cytotoxic effects

In terms of intestinal epithelial barrier protection, coumarins upregulate the expression of tight junction proteins such as occludin and ZO-1, as well as E-cadherin, thereby reducing intestinal epithelial permeability (Witaicenis et al., 2018)

To evaluate the consequences of GSH depletion per se on the TNBS+ethanol-induced injury, additional groups of rats were treated with DEM