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The GRAS determination was likely based on the compound's limited systemic absorption (when ingested), short plasma half-life, and lack of acute toxicity signals in the Phase 2b obesity trial

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Specifically, it is involved in the metabolism of carbohydrates, fats, and proteins, which are the main sources of energy for the body

A vitamin B12 deficiency can reduce the number of white blood cells, thereby weakening the immune system