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PMID: 3957720 Rottner M, Freyssinet J-M, Martinez M.C

Daniel, D

The chemical site of action is the reactive thiol group on the cysteine residue

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These strains are classified as variants of concern (VOCs) [17], as the N501Y mutation present in variants from the UK (Alfa), South Africa (Beta), and Brazil (Gamma) that has shown an increase in ACE2 affinity causing enhanced infectivity and more severe COVID-19 [8, 18]