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Furthermore, GA enhanced endothelial function, inhibited platelet aggregation and thrombosis, reduced abnormal vascular smooth muscle cell proliferation, and stabilized atherosclerotic plaques, comprehensively addressing the pathological processes of ASCVD

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B12 supplementation decisions should be individualized based on baseline risk factors, clinical presentation, and laboratory findings rather than routine supplementation for all Zepbound users

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KhachaneYKozlowskaKSavageBMcClureGButlerGGrayNet al

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Through the selective clearance of damaged mitochondria, mitophagy reduces the production of ROS, thereby protecting cells from oxidative damage [16]

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Numerous studies indicate that the composition of immune cells in the TME, particularly endogenous immune cells (such as MDSCs, Tregs and M2 macrophages), is directly associated with unfavorable tumor treatment outcomes (130-132)

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