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In the present study, mTOR/S6K activation was observed in kidney tissues of diabetic mice and HG-treated HRMC cells, as indicated by the high phosphorylation of S6K with Western blotting, which was effectively inhibited by HU treatment

Due to the limited availability of early diagnostic techniques and the prevalence of chemotherapy resistance, the overall survival rate for individuals with advanced OC remains considerably low

Liposomes: from Bangham to supercritical fluids

Moench) and antiproliferative activity in vitro of four main components identified

Melanoma Management Publicatie weergeven Opinion article on the use of cell penetrating peptides against metastatic melanoma, in this case highlighting the druggable potential of an interaction between to players important to melanoma progression: Pin1 and FOXM1 Targeted inhibition of metastatic melanoma through interference with Pin1-FOXM1 signaling Oncogene Melanoma is the most lethal form of skin cancer and successful treatment of metastatic melanoma remains challenging

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