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doi: 10.1161/CIRCHEARTFAILURE.118.005418

But I am clear that mental health claims are speculative, and choosing it specifically for psychiatric benefit is not evidence-based

It is dosed at 10mg twice a day for 8 weeks (this can be further extended for another 8 weeks for a total of 16 weeks if there is partial response), followed by 5mg twice a day for maintenance[102104]