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Living in a rural area, I had been driving a 140 mile round trip each week to get shots administered for a much higher pricetag in a clinic in the city nearest to me

Kidney Load Repeated high doses may strain kidney filtration

Global transcriptomic analysis of endocrine therapy-resistant breast cancer cells revealed that SLC6A14 expression is downregulated under the control of increased miR-23b-3p expression, resulting in increased aspartate and glutamate uptake (Bacci et al., 2019)

That helped some but the benefit was short-lived

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