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Intracellular and extracellular functions of heat shock proteins: repercussions in cancer therapy

Lactate enhances NMNAT1 lactylation to sustain nuclear NAD(+) salvage pathway and promote survival of pancreatic adenocarcinoma cells under glucose-deprived conditions

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Vascular endothelial growth factor (VEGF) and its tyrosine kinase receptor VEGFR support the growth and maintenance of tumor neovasculature necessary for survival and metastasis