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stable split chimerism was achieved, with the reconstitution of the T-cell lineage only, as previously observed in murine experiments (Blazar et al., 1996)

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Animal models of disease are commonly assessed on the basis of three criteria

Papain was also cocrystallized with 1 and analogs using the same protocol as above, with the addition of the chosen inhibitor compound dissolved in solution to the crystallization well

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For instance, thalidomide, which was globally banned in 1960s due to its teratogenic properties, was approved for treating leprosy in 1998 and for multiple myeloma as well in 2006