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Description

Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models

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V.VasconcellosR

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A.AbdallahB

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The Nrf2 Pathway and antioxidant activity Nuclear factor erythroid 2 [NF-E2]-related factor 2, known by the much easier to remember acronym Nrf2 is a transcription factor which is a major regulator of cell protection, including antioxidant, responses

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Over the past decade, the role of miRNAs in VSMC development, phenotypic transformation, and vascular pathology has been widely studied

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As mentioned above, TAMs are major inflammatory cell populations that secrete a variety of inflammatory mediators, such as CCL2 and CXCL8, and maintain tumor proliferation and immunosuppressive phenotype by inducing the transformation of TAMs from pro-inflammatory M1 type to anti-inflammatory M2 type

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