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Description

This mechanism primarily facilitates the rapid clearance of large quantities of cytoskeletal proteinsparticularly myofibrillar and neurofilament componentsand becomes increasingly active compared with the UPS during normal aging (Tedesco et al., 2023)

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Histopathological findings The histology revealed a neoplasm characterized by spindle-shaped and epithelioid cells, featuring nuclei with vesicular chromatin, occasionally evident nucleoli, and amphophilic cytoplasm (see Figure 3)