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Liu PP, Liu J, Jiang WQ, Carew JS, Ogasawara MA, Pelicano H, et al

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During ischemia, LSECs undergo vacuolization and swelling due to energy depletion and ion transport dysfunction, leading to the narrowing of the sinusoidal lumen and obstructing smooth blood flow (47)

Am J Pathol 193:12231233

H.Naghdi BadiH.SkaraA.MehrafarinA.JandaT.GhorbanpourM.et al

Although inhibition of ABCC1 potentiates the effect of BH3 mimetics, combinatorial treatment with ABCC1 - inhibitors and BH3-mimetic drugs is currently not a therapeutic option for patients, as no ABCC1 inhibitor is approved for clinical use