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Effect of IBD on the liver, and liver disease on the gut Influence of IBD on a healthy liver Since the liver receives approximately 70% of its blood supply from the portal vein [70], which drains the gastrointestinal tract [71], IBD is likely to have significant effects on liver function, particularly when there is chronic intestinal inflammation and dysbiosis in IBD (Fig

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In humans, OCT1 is mainly expressed in the sinusoid membrane of hepatocytes, whereas in rodents, OCT1 is strongly expressed in the basolateral membrane of renal proximal tubule cells

PMID 31906370

Br J Cancer