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It was hypothesised that due to an excessive dampening of the of the immune response, there was an increase opportunity for secondary infections (91)

For example, approximately 27% of SCLC has a SOX2 amplification ( Prominent phenotypic features of small cell lung cancer also lack drug therapy alternatives

The analysis of data retrieved from four cancer databases (COSMIC, cBioPortal, ICGC, and TCGA) reveals significantly higher mutation rates for KRAS than for HRAS and NRAS (160)