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found that GluR3 / knockout mice virtually lack electroencephalographic and signatures of NREM sleep and that three of nine GluR3 (/) mice expressed seizure activity during wakefulness and sleep (Steenland et al., 2008)

Couto JP, Daly L, Almeida A, Knauf JA, Fagin JA, Sobrinho-Simes M, et al

PLOS ONE, 13(9), e0204350

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Again, this data is consistent with changes associated with the binding of NADPH proximal to the FAD cofactor and therefore this initial charge transfer absorption has been assigned to occur with the formation of the SmTGRNADPH complex for the oxidized state of the flavin