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Raw reads were trimmed using Trim Galore (v.0.6.6) to remove the adapter sequences

Johns wort ( Hypericum perforatum ) is a flowering plant

Since not all disulfide bonds that are initially formed during de novo folding connect the native cysteine pair, oxidative protein folding also involves the reduction of non-native disulfide bonds and re-formation of the correct ones (i.e., disulfide isomerization)

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