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E CY, Cai Y, Sun BZ, Guan LY, Jiang T

Rafnsson S, Saravanan P, Bhopal R, Yajnik C

Working with an animal model of MS as well as human post-mortem brains, the researchers found that fingolimod suppresses neuroinflammation by functionally and physically regulating B 12 communication pathways, specifically elevating a B 12 receptor called CD320 needed to take up and use needed B 12 when it is bound to TCN2, which distributes B 12 throughout the body, including the CNS