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Thirdly, the current study focused on patients with MoCA scores below 26, and future research would benefit from including SCZ patients with minimal cognitive deficits (MoCA 2730) to provide a more comprehensive understanding of the relationship between ferroptosis markers and cognitive function in SCZ

In thalassemia, unstable globin chains and excess free iron generate reactive oxygen species, which damage red blood cell membranes and shorten their lifespan

AST/Bex also upregulated the expression of ABCA1, LRP1, and/or APOA-I, thereby facilitating cholesterol efflux partially through PPAR/RXR activation, and downregulated cholesterol biosynthesis and esterification

L.EvansA.et al (2014)

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We have created this scoring system, as no such method was previously reported in the literature