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As demonstrated in several earlier studies, oral administration of glutathione does not lead to high enough serum concentration to be of any therapeutic value at all due to extremely poor absorption from the gastrointestinal tract

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American Journal of Physiology-Endocrinology and Metabolism Jornayvaz FR, Jurczak MJ, Lee H-Y, Birkenfeld AL, Frederick DW, Zhang D et al (2010) A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain