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Bromine is an essential trace element for assembly of collagen IV scaffolds in tissue development and architecture

TPP, the biologically active form of thiamine (vitamin B 1 ), is tightly bound to the enzyme and participates in the transfer of activated aldehyde intermediates by stabilizing the two-carbon carbanions formed during the reaction

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The specific role of ACSL4 in human diseases remains unclear, highlighting the need for better understanding its function and significance in relation to ferroptosis