glutathione synthesis in the body Figure 2 from How Do Cells Produce Glutathione?

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3.3.1 Parkinsons disease (PD) The primary pathologic hallmarks of PD are loss of dopaminergic neurons located in an area of the brain called the substantia nigra pars compacta, and the presence of Lewy bodies, intracellular aggregates of misfolded -synuclein, in dopaminergic neurons and likely contribute to the death of these neurons

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-catenin up-regulates Atoh1 expression in neural progenitor cells by interaction with an Atoh1 3 enhancer