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tacrolimus and pimecrolimus bind to the FK506 binding protein), and these medications are used in the management of immune-mediated lesions ( Table 2 )

4 The ferroptosis-immune-metabolic axis in COPD The interplay between ferroptosis, immune dysregulation, and metabolic rewiringcollectively termed the ferroptosis-immune-metabolic axisis a central driver of COPD pathogenesis

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Glutathione is a critical antioxidant found in almost every cell of the body

Exposure of LDL to HOCl leads to its aggregation, followed by rapid uptake and degradation by macrophages [247, 326, 327]