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Presence of 5 alpha-reductase isozymes and aromatase in human prostate cancer cells and in benign prostate hyperplastic tissue

In this state, fibroblasts synthesize fewer ECM proteins, while matrix-degrading metalloproteinases increase, further exacerbating the imbalance in ECM homeostasis and perpetuating the cycle of collagen fiber fragmentation

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Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma

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