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W., Simons, S

Ryanodine receptors (RyRs) are bulky ion channels that release Ca 2+ from an intracellular calcium-storing compartment and play important roles in brain function

Accumulated lactate contributes to cytoplasmic acidosis, prompting cells to activate compensatory mechanisms for exporting excess lactate into the extracellular space and circulation

Slow Recovery: Whether it is after a workout or a long day, a slow "bounce back" time can indicate that your cellular cleanup crew is understaffed

Progressive decrease of melatonin production over consecutive days of simulated night work

14 All of these studies suggest a potential role of progenitor cells in liver regeneration after APAP-induced ALF, which should be explored in future studies from the standpoint of regenerative therapy and biomarker development