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Description

doi: 10.1038/s41598-022-11236-2 Summary Keywords metformin, rectal cancer, colorectal, radiosensitiser, energy metabolism, radioresistance Citation Buckley CE, OBrien RM, Nugent TS, Donlon NE, OConnell F, Reynolds JV, Hafeez A, ORordin DS, Hannon RA, Neary P, Kalbassi R, Mehigan BJ, McCormick PH, Dunne C, Kelly ME, Larkin JO, OSullivan J and Lynam-Lennon N (2023) Metformin is a metabolic modulator and radiosensitiser in rectal cancer

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Vzquez-Meza H, Vilchis-Landeros MM, Vzquez-Carrada M, Uribe-Ramrez D, Matuz-Mares D

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Beclin-1 Overexpression in cases with resected stage II and stage III colon carcinomas, who received 5-FU-based therapy was associated with worse OS, denoting a potential effect of autophagy in drug resistance (29)

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We also analyzed the levels of aspartate transaminase (AST) and alanine transaminase (ALT) after hepatocyte injury

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