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In HaCaT model, quercetin treatment was associated with increased expression of E-cadherin and occludin, upregulation of antioxidant enzymes including superoxide dismutase 1 (SOD1) and superoxide dismutase 2 (SOD2) and catalase, and reduced levels of pro-inflammatory cytokines and matrix metalloproteinases (MMPs), which may support improved keratinocyte migration and in vitro wound closure (Beken et al., 2020)

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